Regenerative therapy for spinal cord injury using iPSC technology
نویسندگان
چکیده
منابع مشابه
iPSC technology‐based regenerative therapy for diabetes
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), into pancreatic endocrine lineages has been vigorously examined by reproducing the in vivo developmental processes of the pancreas. Recent advances in this research field have enabled the generation from hESCs/iPSCs of functionally mature β-like cells i...
متن کاملCell Therapy in Spinal Cord Injury: a Mini- Reivew
Spinal cord injury (SCI) is a debilitating disease which leads to progressive functional damages. Because of limited axonal regeneration in the central nervous system, there is no or little recovery expected in the patients. Different cellular and molecular approaches were investigated in SCI animal models. Cellular transplantation of stem cells can potentially replace damaged tissue and provid...
متن کاملStem Cells Therapy for Spinal Cord Injury.
Spinal cord injury (SCI), a serious public health issue, most likely occurs in previously healthy young adults. Current therapeutic strategies for SCI includes surgical decompression and pharmacotherapy, however, there is still no gold standard for the treatment of this devastating condition. Inefficiency and adverse effects of standard therapy indicate that novel therapeutic strategies are req...
متن کاملPharmacological Therapy for Acute Spinal Cord Injury.
• Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. Clinicians considering MP therapy should bear in mind that the drug is not Food and Drug Administration (FDA) approved for this application. There is no Class I or Class II medical evidence supporting the clinical benefit of MP in the treatment of acute SCI. Scattered reports of C...
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ژورنال
عنوان ژورنال: Inflammation and Regeneration
سال: 2020
ISSN: 1880-8190
DOI: 10.1186/s41232-020-00149-0